STAT3正向调控正畸牙移动速率与牙槽骨骨量

张程,陶贵渝,黄鹂,吕春晓,李天成,尹星,邹淑娟

Signal transducer and activator of transcription 3 positively modulates orthodontic tooth movement speed and alveolar bone mass

Cheng ZHANG,Guiyu TAO,Li HUANG,Chunxiao LV,Tiancheng LI,Xing YIN,Shujuan ZOU

表2 2组大鼠7 d、14 d上颌第一磨牙根分叉处牙槽骨微结构micro-CT测量值

Table 2 Micro-CT measurements of the alveolar bone microstructure of the upper first molars at the bifurcation on day 7 and day 14 in two groups of rats x ± s

Parameters Days Control group Test group P t BV/TV（%） 7 0.597 ± 0.032 0.575 ± 0.063 0.490 0.72 14 0.533 ± 0.028 0.455 ± 0.030 0.003 3.81 Tb.N（1/mm） 7 8.290 ± 0.599 7.920 ± 0.443 0.286 1.13 14 7.970 ± 0.591 7.090 ± 0.491 0.028 2.57 Tb.Th（mm） 7 0.095 ± 0.012 0.095 ± 0.010 0.982 0.02 14 0.085 ± 0.006 0.069 ± 0.008 0.006 3.44 Tb.Sp（mm） 7 0.090 ± 0.015 0.098 ± 0.013 0.421 0.84 14 0.092 ± 0.016 0.116 ± 0.012 0.025 2.63 BMD（g/cc） 7 1.100 ± 0.085 1.060 ± 0.080 0.442 0.80 14 1.030 ± 0.075 0.902 ± 0.067 0.016 2.89