miR-135b-5p在口腔鳞状细胞癌中的表达及相关生物信息学分析

赵格, 黎昌学, 郭超, 朱慧

Expression and relevant bioinformatics analysis of miR-135b-5p in oral squamous cell carcinoma

ZHAO Ge, LI Changxue, GUO Chao, ZHU Hui

表3 miR-135b-5p靶基因KEGG信号通路显著性富集分析结果

Table 3 Significantly enriched KEGG pathways of target genes of miR-135b-5p

ID Description P Target gene ID hsa05032 Morphine addiction < 0.001 PDE1C/GNG7/PDE3B/GABRB2/PDE7B hsa04020 Calcium signaling pathway < 0.001 ATP2B3/PDE1C/ERBB4/CACNA1D/ATP2B2 hsa04726 Serotonergic synapse < 0.001 GNG7/SLC6A4/GABRB2/CACNA1D hsa04723 Retrograde endocannabinoid signaling < 0.001 GNG7/RIMS1/GABRB2/CACNA1D hsa04924 Renin secretion 0.001 PDE1C/PDE3B/CACNA1D hsa04022 cGMP-PKG signaling pathway 0.001 ATP2B3/PDE3B/CACNA1D/ATP2B2 hsa04727 GABAergic synapse 0.002 GNG7/GABRB2/CACNA1D hsa04925 Aldosterone synthesis and secretion 0.003 ATP2B3/CACNA1D/ATP2B2 hsa04024 cAMP signaling pathway 0.004 ATP2B3/PDE3B/CACNA1D/ATP2B2 hsa04724 Glutamatergic synapse 0.005 GRIK3/GNG7/CACNA1D