图4. 蛋白互作网络的关键靶基因

Figure 4. Hub genes of protein-protein interaction network
Ten hub genes were screened by Cytoscape software: the darker the color, the more important the function in the interaction. DLG2: discs-large homolog 2; ANK3: ankyrin repeat 3; ERBB4: erb-B2receptor tyrosine kinase 4; SCN2B: sodium channel voltage-gated type II beta; NBEA: neurobeachin; GABRB2: γ-aminobutyric acid neurotransmitter receptor β2 subunit gene; ATP2B2: plasma membrane calcium ATPase 2; SNTA1: α-syntrophin; CACNA1D: calcium voltage-gated channel subunit alpha1 D; SPTBN4: spectrin beta non-erythrocytic 4; UTRN: background Utrophin; DTNA: dystrobrevin-α; RIMS1: rab-interacting molecules 1; SLC6A4: solute carrier family 6 member 4; ATP2B3: plasma membrane calcium ATPase 3; GNG7: guaninenucleotide-binding protein γ-7; KCNB1: voltage-gated potassium channel sub-family B member 1; GRIK3: glutamate ionotropic receptor Kainate type subunit 3; PGR: epithelial progesterone receptor; SHISA6: shisa family member 6; PRLR: prolact inreceptor; DCLK1: doublecortin-like kinase1; CTTNBP2: cortactin binding protein 2